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In bacteria, protists, fungi, plants and melatonin indirectly

In bacteria, protists, fungi, plants and melatonin indirectly with tryptophan as an intermediary for the path of shikimic acid product. Synthesis in these cells begins with the D-erythrose--phosphate and Alvesvoainol, and photosynthetic cells with carbon dioxide. The rest of the reactions are similar, but with slight differences in the past two enzymes.  

 

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In vertebrates, and it regulates the secretion of melatonin by norepinephrine. Raises norepinephrine concentration camp Marz Sleep Sprays inside cells by the beta-adrenergic receptors and activates protein kinase-dependent Camp (PKA). PKA phosphorylates the enzyme before the last, and arylalkylamine N- acetylcysteine ​​(AANAT). The exposure (day) light, stop stimulus Norodrini, protein and destroyed immediately by the proteasomal proteolysis.  and it began production of melatonin again in the evening at a point called the dim light melatonin (DLMO).

 

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