Tweezers

[Mavis Watts]

Visual tweezers (OT) have appeared as an important tool for influencing individual biological cells and performing superior biophysical/biomechanical characterizations. Distinct features of using tweezers for these characterizations include non-contact force for cell manipulation, force decision as accurate as 100aN and amiability to liquid medium conditions. Their wide selection of applications, such as for example taking foreign products into individual cells, delivering cells to specific areas and selecting cells in microfluidic systems, are analyzed in this essay. New developments of OT for nanomechanical characterization of varied biological cells are discussed with regards to both their theoretical and experimental developments. The near future trends of employing OT in single cells, especially in stem cell shipping, tissue engineering and regenerative medicine, are prospected. More to the point, current limitations and future challenges of OT for these new paradigms may also be outlined in this review.

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