There are some people who can greatly benefit from these new drugs. People who can not tolerate statins because of the potential to take advantage of new drugs side effects. According to clinical trials 50% reduction in total cholesterol and cholesterol, and cholesterol levels relatively after using the drug for a few months.
The only patients who overgrowth of blood family who will benefit from new cholesterol drugs are those with one copy of the gene that causes the disease. They have some LDL receptor, and drugs that help preserve them. People with two copies of the gene family of hyper blood cholesterol, but they do not have LDL receptors that are preserved and not to respond to new drugs.